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IONIS PHARMACEUTICALS INC (IONS) Institutional Holdings & 13F Ownership
Ionis Pharmaceuticals, Inc., a commercial-stage biotechnology company, provides RNA-targeted. Review IONS institutional holders, 13F ownership, and position changes on Finoriq.
Company Snapshot
Ionis Pharmaceuticals, Inc., a commercial-stage biotechnology company, provides RNA-targeted medicines in the United States. The company offers TRYNGOLZA reduces triglyceride levels in adults with familial chylomicronemia syndrome (FCS) and acute pancreatitis; DAWNZERA for prophylaxis to prevent attacks of hereditary angioedema in adults; WAINUA for the treatment of the polyneuropathy of hereditary transthyretin-medicated amyloidosis (ATTRv-PN) in adults; and SPINRAZA for pediatric and adult patients with spinal muscular atrophy (SMA). It also provides QALSODY for the treatment of Amyotrophic Lateral Sclerosis (ALS); TEGSEDI for the treatment of ATTRv-PN in adults; and WAYLIVRA for treatment for FCS and familial partial lipodystrophy. It also develops products under Phase 3 clinical trials, such as Olezarsen for patients with hypertriglyceridemia (SHTG) and cardiovascular disease (CVD); and Zilganerse, a potential treatment for people with genetically confirmed Alexander disease, as well as ION582 which is in Phase 3 clinical trial for the potential treatment of AS, a rare genetic neurological disease. In addition, the company develops Eplontersen to degrade mutant and wild-type TTR mRNA through binding to the TTR mRNA; Pelacarsen to inhibit the production of apolipoprotein(a) in the liver to offer a direct approach for reducing lipoprotein(a); Bepirovirsen to inhibit the production of viral proteins associated with hepatitis B virus; Sefaxersen to reduce the production of complement factor B and lower activation of the alternative complement pathway; and Ulefnersen to reduce the production of the fused in sarcoma, as well as other mid-stage pipeline investigational medicines. It has a strategic collaboration with Biogen for the treatment of neurological disorders; and collaboration and license agreement with GSK, AstraZeneca, Novartis, and Roche, as well as with Metagenomi. The company was incorporated in 1989 and is headquartered in Carlsbad, California.
- Company
- IONIS PHARMACEUTICALS INC (IONS)
- Ticker
- IONS
- Market Cap
- $8.8B
- Latest Price
- $53.12
- Industry
- Biotech & Pharma
IONIS PHARMACEUTICALS INC (IONS) Top Institutional Holders
Top current 13F holders indexed for IONIS PHARMACEUTICALS INC (IONS). Latest period 2026-03-31.
| Rank | Investor | Value | Portfolio | Filing |
|---|---|---|---|---|
| 1 | Tweedy BrowneCIK 0000732905 | $170.9M | 13.6% | Filing2026-05-06 |
| 2 | Ken FisherCIK 0000850529 | $10.6M | 0.0% | Filing2026-05-05 |
| 3 | Joel GreenblattCIK 0001510387 | $7.4M | 0.02% | Filing2026-05-15 |
| 4 | Ron BaronCIK 0001017918 | $3.4M | 0.01% | Filing2026-05-15 |
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